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proximal tubule epithelial cell line ok  (ATCC)


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    Structured Review

    ATCC proximal tubule epithelial cell line ok
    Fig. 6 Inhibition of STAT3 attenuates tubular <t>epithelial</t> cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001
    Proximal Tubule Epithelial Cell Line Ok, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 159 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/proximal+tubule+epithelial+cell+line+ok/OK/pm39367511-110-9-20
    Average 94 stars, based on 159 article reviews
    proximal tubule epithelial cell line ok - by Bioz Stars, 2026-09
    94/100 stars

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    1) Product Images from "STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation."

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.

    Journal: Cell communication and signaling : CCS

    doi: 10.1186/s12964-024-01841-1

    Fig. 6 Inhibition of STAT3 attenuates tubular epithelial cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001
    Figure Legend Snippet: Fig. 6 Inhibition of STAT3 attenuates tubular epithelial cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

    Techniques Used: Inhibition, Co-Culture Assay, Western Blot, Expressing, Cell Culture

    Related Articles

    Inhibition:

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL-1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Co-Culture Assay:

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL-1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Western Blot:

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL-1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Expressing:

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL-1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Cell Culture:

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL-1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).. RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).RAW264.7 cells were cultured in Dulbecco’s Modified Eagle’s medium (DMEM, cat. L0103, BioWest, Nuaillé, France), and OK cells were cultured in Minimum Essential Medium Eagle (MEM, cat. M4655, Sigma-Aldrich).



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    ATCC proximal tubule epithelial cell line ok
    Fig. 6 Inhibition of STAT3 attenuates tubular <t>epithelial</t> cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001
    Proximal Tubule Epithelial Cell Line Ok, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/proximal+tubule+epithelial+cell+line+ok/OK/pm39367511-110-9-20
    Average 94 stars, based on 1 article reviews
    proximal tubule epithelial cell line ok - by Bioz Stars, 2026-09
    94/100 stars
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    Fig. 6 Inhibition of STAT3 attenuates tubular epithelial cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

    Journal: Cell communication and signaling : CCS

    Article Title: STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation.

    doi: 10.1186/s12964-024-01841-1

    Figure Lengend Snippet: Fig. 6 Inhibition of STAT3 attenuates tubular epithelial cell injury in a co-culture system with macrophages. A A schematic illustration of co-culture system with macrophages and tubular epithelial cells. B Western blot results of IL-6, KIM-1, pSTAT3, and STAT3 expression in RAW264.7 and OK cells are shown. C Upregulated expression of KIM-1 in OK cells co-cultured with LPS-stimulated RAW264.7 cells significantly decreased upon pre- and concomitant-treatment of 2 μM Stattic. All experiments were independently replicated at least three times, and the data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

    Article Snippet: The murine macrophage cell line RAW264.7 (TIB-71) and the proximal tubule epithelial cell line OK (CRL1840) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA).

    Techniques: Inhibition, Co-Culture Assay, Western Blot, Expressing, Cell Culture